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Liothyronine Sodium

 

 

 

 

 

Liothyronine sodium is a synthetic preparation of T3, and can be purchased in oral (Cytomel) and intravenous (Triostat) formulations.  Cytomel tablets are intended for oral administration only; once-a-day dosage is recommended.  Cytomel tablets are liothyronine sodium are available in mcg, 25 mcg and 50 mcg.  Liothyronine sodium has a rapid cutoff of activity which permits quick dosage adjustment and facilitates control ofthe effects of overdosage, should they occur.  Liothyronine Sodium (Cytomel) [T3]Cytomel (liothyronine sodium)

Cytomel is not an anabolic/androgenic steroid but a thyroid hormone.  Liothyronine sodium is also more potent and has a more rapid action than thyroxine (T4). 

Liothyronine sodium injection (T3) can be used in patients allergic to desiccated thyroid or thyroid extract derived from pork or beef.  Liothyronine sodium injection (T3) should normally be administered at least four hours-and not more than 12 hours-apart. 

Liothyronine Sodium is made by SmithKline, called Cytomel which is it's brand name.  Liothyronine sodium can also be used therapeutically in the treatment of thyrotoxicosis as an adjunct to carbimazole in order to prevent subclinical hypothyroidism developing during treatment. 

Liothyronine sodium may be preferred for treating severe and acute hypothyroid states because of its rapid, and more potent effect, but thyroxine sodium is normally the drug of choice for routine replacement therapy.  Liothyronine sodium should be given in divided doses two or three times daily.  Liothyronine sodium is contraindicated in patients with cardiovascular disorders or angina of effort.