Liothyronine
Sodium
Liothyronine
sodium is a
synthetic preparation of T3, and can be purchased in oral (Cytomel) and
intravenous (Triostat) formulations. Cytomel tablets are
intended for oral administration only; once-a-day dosage is
recommended. Cytomel tablets are liothyronine sodium are
available in mcg, 25 mcg and 50 mcg. Liothyronine sodium
has a rapid cutoff of activity which permits quick dosage
adjustment and facilitates control ofthe effects of overdosage,
should they occur. Liothyronine Sodium (Cytomel)
[T3]Cytomel (liothyronine sodium)
Cytomel is not an anabolic/androgenic steroid
but a thyroid hormone. Liothyronine sodium is also more
potent and has a more rapid action than thyroxine
(T4).
Liothyronine sodium
injection (T3) can be used in patients allergic to
desiccated thyroid or thyroid extract derived from pork or
beef. Liothyronine sodium injection (T3) should normally
be administered at least four hours-and not more than 12
hours-apart.
Liothyronine
Sodium is made by SmithKline, called Cytomel which is
it's brand name. Liothyronine sodium can also be
used therapeutically in the treatment of thyrotoxicosis
as an adjunct to carbimazole in order to prevent
subclinical hypothyroidism developing during
treatment.
Liothyronine
sodium may be
preferred for treating severe and acute hypothyroid states
because of its rapid, and more potent effect, but thyroxine
sodium is normally the drug of choice for routine replacement
therapy. Liothyronine sodium should be given in divided
doses two or three times daily. Liothyronine sodium is
contraindicated in patients with cardiovascular disorders or
angina of effort.
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